MOTU M6 vs RME Fireface UFX III

Last updated: October 14, 2026

Short answer: the MOTU M6. It ranks #5 of 17 audio interfaces by measured performance, rated 3.8/5, at $449.95; the RME Fireface UFX III ranks #9, rated 3.7/5, and costs $3,199, which makes this an easy call rather than a real tradeoff.

MOTU M6 vs RME Fireface UFX III

What the MOTU M6 does well: Audio Science Review measured 112 dB SINAD from its ESS Sabre32 Ultra DAC, clean for nearly all listening. The catch: MOTU doesn’t publish a 32 ohm headphone power figure, and Audio Science Review found the headphone output poor into low impedance loads and its recording converter weaker than its DAC.

The case for the RME Fireface UFX III: Audio Science Review measured 110 dB SINAD, clean for nearly all listening. The catch: RME doesn’t publish a 32 ohm headphone power figure, so its ability to drive demanding headphones is unknown.

Buy the MOTU M6. It is rated higher than the RME Fireface UFX III and costs less, which makes it the one to get unless you need something the other one does better.

Want more options? Browse the full Headphone Amps and DACs rankings.

Specifications Side By Side

MOTU M6 RME Fireface UFX III
Price$449.95$3,199.00
Ranked#5 of 17 in Audio Interfaces#9 of 17 in Audio Interfaces
Device TypeAudio interfaceAudio interface
SINAD112 dB (measured by Audio Science Review)110 dB (measured by Audio Science Review)
Inputs4 XLR/TRS combo (mic/line/Hi-Z), 2 balanced 6.35 mm line, USB-C, MIDI in-
Outputs4 balanced TRS line outs, 2 headphone, MIDI out-
Headphone Outputs2 x 6.35 mm2 x 6.35 mm
Balanced OutputYes (TRS monitor outs)-
DAC ChipESS Sabre32 Ultra-
Volume ControlHardware knob-
Dimensions9.2” x 4.7” x 1.8” (234 x 120 x 46 mm)17.3” x 1.7” x 8.3” (440 x 44 x 210 mm) (without rack ears)
Weight2.1 lbs (975 g)6.2 lbs (2.8 kg)
Equalizer-Yes (TotalMix FX DSP)

More top alternatives to MOTU M6:

Prices on this page were last checked October 13, 2026 at 3:17 PM UTC. Product prices and availability are accurate as of that date/time and are subject to change; the price and availability shown on Amazon at the time of purchase will apply to the purchase of this product.

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The Two Amps and DACs In Full

MOTU M6: $449.95 Amazon $449.95 eBay

MOTU M6 ranking card

Pros: Audio Science Review measured 112 dB SINAD from its ESS Sabre32 Ultra DAC, clean for nearly all listening. It offers four XLR/TRS combo inputs for mic, line or instrument, two more balanced line inputs, four balanced TRS outputs, two headphone outputs, MIDI in and out and a hardware volume knob.

Cons: MOTU doesn’t publish a 32 ohm headphone power figure, and Audio Science Review found the headphone output poor into low impedance loads and its recording converter weaker than its DAC. The Topping E2x2 rates higher for much less if you only need two inputs.

Released2022 (4 years ago)
Balanced OutputYes (TRS monitor outs)
DAC ChipESS Sabre32 Ultra
Device TypeAudio interface
Dimensions9.2” x 4.7” x 1.8” (234 x 120 x 46 mm)
Headphone Outputs2 x 6.35 mm
Inputs4 XLR/TRS combo (mic/line/Hi-Z), 2 balanced 6.35 mm line, USB-C, MIDI in
Outputs4 balanced TRS line outs, 2 headphone, MIDI out
SINAD112 dB (measured by Audio Science Review)
Volume ControlHardware knob
Weight2.1 lbs (975 g)

RME Fireface UFX III: $3,199.00 Amazon $3,199.00 eBay

RME Fireface UFX III ranking card

Pros: Audio Science Review measured 110 dB SINAD, clean for nearly all listening. It has two 6.35 mm headphone outputs and TotalMix FX DSP with built in EQ, in a full rack width chassis.

Cons: RME doesn’t publish a 32 ohm headphone power figure, so its ability to drive demanding headphones is unknown. It is large and heavy at 2.8 kg, and for playback it rates below the MOTU M6, which measures slightly cleaner for a small fraction of the cost.

Device TypeAudio interface
Dimensions17.3” x 1.7” x 8.3” (440 x 44 x 210 mm) (without rack ears)
EqualizerYes (TotalMix FX DSP)
Headphone Outputs2 x 6.35 mm
SINAD110 dB (measured by Audio Science Review)
Weight6.2 lbs (2.8 kg)