Shure SE425 vs Etymotic ER4SR

Last updated: October 11, 2026

Short answer: the Shure SE425, though neither ranks well in its class. It ranks #434 of 450 in-ear headphones by sound quality, rated 1.9/5, at $299; the Etymotic ER4SR ranks #440, rated 1.7/5, and costs $299.99, so there is not much of a tradeoff to weigh. Both are rated below 3.0/5 among the 450 in-ear headphones, and the Truthear Nova, ranked #2 at $169.99, is a better place to start if sound quality matters.

Shure SE425 vs Etymotic ER4SR

The case for the Shure SE425: Two balanced armature drivers with a 22 ohm impedance and 109 dB/mW sensitivity, so it plays loud from a phone without an amplifier. The catch: A preference score of 48 in crinacle’s measurement places its tuning far from what most listeners prefer, so expect a clearly colored sound.

The case for the Etymotic ER4SR: For listeners who prefer a flat, studio style sound, the midrange from 200 Hz to 3 kHz stays within about 1 dB of target and its largest upper range peak is only 1.6 dB, so vocals come through clear without any glare. The catch: Sub-bass sits about 11 dB below target and falls 6 dB short at 75 Hz, so bass heavy music sounds lean and lacks impact.

Buy the Shure SE425. It is rated higher for sound quality than the Etymotic ER4SR and costs less, which makes it the one to get unless you need something the other one does better.

Still deciding? The full Headphones rankings cover every ranked option.

Specifications Side By Side

Shure SE425 Etymotic ER4SR
Price$299.00$299.99
Ranked#434 of 450 in In-Ear Headphones#440 of 450 in In-Ear Headphones
Form FactorIn-earIn-ear
BackClosedClosed
Harman Preference Score48 (measured by crinacle, via AutoEQ)45 (measured by oratory1990, via AutoEQ)
Deviation From Target4.17 dB standard deviation4.26 dB standard deviation
Tonal Tilt+0.59 (negative is warmer, positive brighter)+1.38 (negative is warmer, positive brighter)
ConnectionWiredWired
Driver TypeBalanced armatureBalanced armature
Drivers2 x balanced armature1 x balanced armature
Impedance22 ohms45 ohms
Sensitivity109 dB SPL/mW98 dB/mW
Frequency Response20Hz - 19kHz (Manufacturer specified)20Hz - 16kHz (Manufacturer specified)
Sub-bass Extension-Falls 6 dB below target at 75 Hz (-10.6 dB at 30 Hz)
Built-in Microphone-No

More worthwhile head-to-heads for Shure SE425:

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The Two Headphones In Full

Shure SE425: $299.00 B&H Photo Video eBay

Shure SE425 ranking card

Pros: Two balanced armature drivers with a 22 ohm impedance and 109 dB/mW sensitivity, so it plays loud from a phone without an amplifier. It is rated above the Etymotic ER4SR at the same price and the Westone W10.

Cons: A preference score of 48 in crinacle’s measurement places its tuning far from what most listeners prefer, so expect a clearly colored sound. It is wired only, with no wireless features or microphone remote listed.

Released2010 (16 years ago)
BackClosed
ConnectionWired
Deviation From Target4.17 dB standard deviation
Driver TypeBalanced armature
Drivers2 x balanced armature
Form FactorIn-ear
Frequency Response20Hz - 19kHz (Manufacturer specified)
Harman Preference Score48 (measured by crinacle, via AutoEQ)
Impedance22 ohms
Sensitivity109 dB SPL/mW
Tonal Tilt+0.59 (negative is warmer, positive brighter)
EQ preset to match the Harman target

Set a preamp of -6.6 dB, then add these filters in any parametric equalizer (Wavelet, Equalizer APO, Peace, or a player with parametric EQ). Calculated by AutoEQ from its measured frequency response.

FilterFrequencyGainQ
Low shelf105 Hz+6.0 dB0.70
Peak223 Hz-3.2 dB0.57
Peak8,943 Hz+6.2 dB1.83
Peak48 Hz+0.8 dB1.86
Peak5,492 Hz+5.0 dB3.43
High shelf10,000 Hz+5.8 dB0.70
Peak3,734 Hz-2.7 dB4.45
Peak2,114 Hz+1.2 dB2.77
Peak9,102 Hz-3.1 dB5.33
Peak895 Hz+0.7 dB2.99

Etymotic ER4SR: $299.99 B&H Photo Video eBay

Etymotic ER4SR ranking card

Pros: For listeners who prefer a flat, studio style sound, the midrange from 200 Hz to 3 kHz stays within about 1 dB of target and its largest upper range peak is only 1.6 dB, so vocals come through clear without any glare. It is rated level with the Audio-Technica ATH-E70 and Mackie MP-360, which cost more.

Cons: Sub-bass sits about 11 dB below target and falls 6 dB short at 75 Hz, so bass heavy music sounds lean and lacks impact. Treble about 6 dB low from 6 to 10 kHz and a 9 dB dip near 11.7 kHz take away air and shimmer. Its 98 dB/mW sensitivity is on the low side for an in ear, so it needs more volume than most.

Released2016 (10 years ago)
BackClosed
Built-in MicrophoneNo
ConnectionWired
Deviation From Target4.26 dB standard deviation
Driver TypeBalanced armature
Drivers1 x balanced armature
Form FactorIn-ear
Frequency Response20Hz - 16kHz (Manufacturer specified)
Harman Preference Score45 (measured by oratory1990, via AutoEQ)
Impedance45 ohms
Sensitivity98 dB/mW
Sub-bass ExtensionFalls 6 dB below target at 75 Hz (-10.6 dB at 30 Hz)
Tonal Tilt+1.38 (negative is warmer, positive brighter)
EQ preset to match the Harman target

Set a preamp of -6.0 dB, then add these filters in any parametric equalizer (Wavelet, Equalizer APO, Peace, or a player with parametric EQ). Calculated by AutoEQ from its measured frequency response.

FilterFrequencyGainQ
Low shelf105 Hz+6.0 dB0.70
Peak2,470 Hz-3.7 dB0.94
Peak7,389 Hz+6.4 dB1.15
Peak77 Hz+1.2 dB2.20
Peak1,450 Hz-1.8 dB2.27
High shelf10,000 Hz+2.5 dB0.70
Peak269 Hz-0.5 dB1.17
Peak745 Hz+0.5 dB2.09
Peak7,552 Hz-0.8 dB4.20
Peak9,634 Hz-1.0 dB5.99