Short answer: neither is clearly better, so buy on price. The Onn Large Party gen 2 is an insane value speaker, though it is not quite as loud as the old one. The Harman Kardon Onyx Studio 6 is warm with boosted bass and runs 8 hours at medium volume, and at $130 against $129 the two are effectively the same money. The Harman Kardon Onyx Studio 6 is discontinued; its replacement is the Harman Kardon Onyx Studio 9.

Buy the Harman Kardon Onyx Studio 6 ($130) for a boombox speaker; the Onn Large Party gen 2 ($129) suits a party speaker instead.
There is a real gap in water resistance: the Harman Kardon Onyx Studio 6 at IPX7 (brief submersion) against the Onn Large Party gen 2, which has IPX4 (splashing).
Want more options? Browse the full Portable Bluetooth rankings.
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Specifications Side By Side
| Harman Kardon Onyx Studio 6 | Onn Large Party gen 2 | |
|---|---|---|
| Price | $130 Discontinued | $129 |
| Ranked | #13 of 113 in Boombox Size Portable Bluetooth Speakers | #17 of 53 in Party Size Portable Bluetooth Speakers |
| Aux Input | Yes | Yes |
| Bass Extension (-10dB) | 37Hz | - |
| Battery Life | 8 hours (Manufacturer specified) | 12 hours (Manufacturer specified) |
| Built-in Microphone | Yes | - |
| IP Rating | IPX7 | IPX4 |
| Bluetooth Latency | 180ms | - |
| Maximum SPL | 96dB (measured by Alan Ross Reviews) | - |
| Party Mode | Yes (Wireless Dual Sound) | Yes (Party Sync Mode) |
| Power Input | DC Barrel Connector (19V/2A) | AC Power cord |
| Stereo | No | Partially |
| Omnidirectional | No | No |
| TWS | Yes (see https://www.reddit.com/r/Bluetooth_Speakers/comments/w339x5/how_to_harman_kardon_onyx_studio_5_6_dual_sound/) | No |
| Weight | 6.5 lbs (2.94 kg) | 20.9 lbs (9.5 kg) |
| Bluetooth | Yes | Yes |
| Bluetooth Codecs | SBC | SBC |
| App | No | No |
| EQ | No | No |
| Power Bank | No | Yes (USB-A, 5V/2.1A) |
| USB Playback | No | No |
| Bluetooth Version | 4.2 | - |
| Amplifier Power | 50W RMS | 160W RMS (640W peak) |
| Dimensions | 5” x 11.5” x 11.2” (128 x 291 x 284 mm) | 22.5”H x 11.6”W x 11.8”D (571 x 295 x 300 mm) |
| Drivers | 1x 120mm (4.7”) woofer + 1x 25mm (1”) tweeter + 1x passive radiator | Dual 8” (203mm) woofers + dual tweeters |
| Digital Aux Input | No | No |
| Strap | No | No |
| FM Tuner | - | Yes |
| Guitar Input | - | Yes |
| Microphone Input | - | Yes (Karaoke mode with echo effect) |
| Lights | - | Yes |
| Wheels | - | Yes |
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