Short answer: the PreSonus Eris Studio 5, if you are buying new. The PreSonus Eris E5 ranks higher than the Edifier R1280DB (#77 vs #94 of 108 powered bookshelf speakers) but is discontinued; its replacement, the PreSonus Eris Studio 5, is rated 3.6/5 at $299.98 and is still sold new.

On the Edifier R1280DB side: Excellent bass output and power handling for the price, not bottoming out or distorting even played loud. Set against that: Not quite as neutral sounding as the Edifier MR4.
Buy the PreSonus Eris Studio 5, the replacement for the discontinued PreSonus Eris E5; it is rated higher for sound quality than the Edifier R1280DB.
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Specifications Side By Side
| Edifier R1280DB | PreSonus Eris E5 | |
|---|---|---|
| Price | $189.99 per pair | $186.98 per pair Discontinued |
| Ranked | #94 of 108 in Medium Size Powered Bookshelf Speakers | #77 of 108 in Medium Size Powered Bookshelf Speakers |
| Bass Extension (-3dB) | 63Hz (measured, Audio Science Review) - shares the R1280T driver and cabinet; read from that measurement | - |
| Bass Extension (-10dB) | 53.2Hz (derived, log-interpolated between spinorama.org -9dB/-12dB points) | - |
| Dimensions | 9.2”H x 5.7”W x 7.7”D (233.7 x 144.8 x 195.6 mm) | 10.2”H x 7”W x 7.7”D (259.1 x 177.8 x 195.6 mm) |
| Frequency Response | 55 Hz-20 kHz (-3dB) (Manufacturer specified) | 53Hz - 22kHz (Manufacturer specified) |
| Inputs | Bluetooth, 2x RCA Input, Digital Optical, Digital Coax | TRS, XLR, RCA |
| Outputs | None | - |
| Weight | 10.8 lbs (4.9 kg) | 10.1 lbs (4.6 kg) each |
| Drivers | 4” (102mm) woofer | 5” (127mm) woofer |
| App | No | No |
| Bluetooth | Yes | No |
| Bluetooth Version | 5.1 | - |
| Bluetooth Codecs | SBC (inferred; additional codecs unverified) | - |
| EQ | No | Yes (Room adjustment) |
| Amplifier Power | 42w RMS Total | 80w Per Speaker |
| XLR Input | No | Yes |
| RCA Input | Yes | Yes |
| TRS Input | No | Yes |
| Optical Input | Yes | No |
| Coaxial Input | Yes | No |
| USB Input | No | No |
| HDMI Input | No | No |
| AES Input | No | No |
| Aux Input | No | No |
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